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In MyMemeCards, the meme card game, “Low Cortisol” is a common card of the Memes FR pack, number 5486 of the collection, and the 753rd best-known meme of its 3502 cards. Here is what the meme means, where it comes from, and how to get its card.
What does the “Low Cortisol” meme mean?
The joke is about being almost absurdly unbothered: everything may be going wrong, but the person stays calm. “Low cortisol” turns that composure into a badge of coolness, while the imagined zero level exaggerates the idea for comic effect. People use it to caption a person, scene, or reaction that remains relaxed under pressure. It describes a meme persona, not someone’s actual hormone levels.
Where does the “Low Cortisol” meme come from?
Low Cortisol has no single, firmly established origin. One documented lead connects it to “Cortisol Spike,” a phrase seen on X in late February and early March 2025, around a line about raising someone’s cortisol and making them less beautiful. The phrase was also linked to videos by a Latvian alternative-health influencer whose angry reactions were described as cortisol spikes. Another branch uses an animation of Agnes Tachyon, a character from *Uma Musume: Pretty Derby*. Beankong2 posted the animation on YouTube on January 7, 2026. @gogetachiquito_oficial reposted it on TikTok on January 24, and @quandung0101 posted the earliest known “low cortisol” edit on February 12, 2026. The original show or video featuring a real person is unknown. The format is used on TikTok, X, Reddit, and Instagram.
- late February–early March 2025“Cortisol Spike” appears on X as one lead connected to the meme.
- January 7, 2026Beankong2 posts an Agnes Tachyon animation on YouTube.
- January 24, 2026@gogetachiquito_oficial reposts the animation on TikTok.
- February 12, 2026@quandung0101 posts the earliest known “low cortisol” edit.
How to use the “Low Cortisol” meme
- Caption a chaotic scene where someone stays completely unbothered.
- Describe a calm reaction to stressful news as “low cortisol.”
- Pair the phrase with a relaxed character image to signal maximum aura.
Also searched as
- Cortisol Spike
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The “Low Cortisol” card in MyMemeCards
| Number | No. 5486 |
|---|---|
| Rarity | Common |
| Collection | Memes FR pack |
| Fame | 50/100 · #753 of 3502 |
| Recycle value | 5 MemeCoins (15 in Shiny) |
| Suggested by | @blair |
How to get the “Low Cortisol” card
Every pack holds 5 meme cards, the first 3 of them Common; Low Cortisol comes out of the Memes FR pack as a common card. The pack odds say what each rarity weighs.
Your first pack is free and needs no account. After that a new free pack lands every 10 minutes, up to 3 waiting for you. You can also buy the card with MemeCoins on the market, bid for it at auction, or trade it — and a double recycles into 5 MemeCoins.
Open your free pack
5 meme cards, one of them at least Rare. One free pack per person.
Free · no account needed
Odds per card, averaged over a pack: Common 72%, Rare 23.9%, Epic 3.2%, Legendary 0.56%, Mythic 0.3%, Full Art ≤ 0.1%, Shiny 0.2%. Cards 1 to 3 are always Common, cards 4 and 5 climb the rarities. Rates drop for cards that circulate a lot. Details
Memes like “Low Cortisol”
More cards of the Memes FR pack
Frequently asked questions
What does “Low Cortisol” mean?
In the meme, it is slang for being calm and barely reacting to stress. The idea of cortisol at zero is an exaggeration, not a medical reading.
Where did the “Low Cortisol” meme come from?
It has no single confirmed origin. One strand is linked to “Cortisol Spike” on X, while another uses an Agnes Tachyon animation.
Who is Agnes Tachyon in the “Low Cortisol” meme?
Agnes Tachyon is a character from *Uma Musume: Pretty Derby*. An animation featuring her was reused in one branch of the meme.
Is “Low Cortisol” a medical term?
In this meme, it is internet slang for an unbothered attitude. It is not a diagnosis.
How do I get the Low Cortisol meme card?
Open a pack of MyMemeCards: “Low Cortisol” is a common card of the Memes FR pack. Your first pack is free, with no account, and you can also buy, trade or win the card at auction.
How rare is the Low Cortisol card?
It is a Common card. Rarity decides which pack slot can deal it, and what it is worth on the market.
Sources: What does the “low cortisol/high cortisol” meme even mean? · Cortisol Level / Cortisol Spike | Know Your Meme · Add the Cortisol Meter to Any Clip | Nemovideo · checked on November 4, 2026.
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Want Low Cortisol in your collection?
Open your free pack: 5 meme cards, no account needed.